Everyday RNA is a Book Written for Everyone

Have you ever wondered "What is RNA?", "What does it do in our cells?", and "How it is being used to make new medicines, including vaccines?" If so, this is the book for you. Everyday RNA presents the science behind RNA in a way that is accessible to everyone—not just specialists with advanced degrees. Available soon from the following retailers:

Amazon Barnes & Noble World Scientific
I

An RNA Primer

The first section describes the major types of RNA found in our cells. By the time you are done reading this section you will understand the difference between DNA and RNA, what genes are, how they are decoded, what a mutation is, and how mutations can lead to disease. No prior training in molecular biology necessary.

II

Emerging RNA Therapeutics

This section describes the history and development of ASO, RNAi, and mRNA therapeutics. It describes the diseases that are being treated by RNA therapeutics in the clinic today. It also compares the general principles of biological and informational therapeutics to traditional small molecule drugs.

III

RNA-guided Genome Editing

The final section describes research in the field of RNA-guided genome editing, focusing on the application of CRISPR to correct errors in the genome and cure heritable disease. This section also describes ethical and regulatory frameworks for this work, and provides a vision for the future of RNA medicine.

About the Author

Sean P. Ryder, Ph.D. graduated summa cum laude from the University of New Hampshire in 1995 with a B.Sc. in Biochemistry. He studied the mechanisms of RNA folding and catalysis in the Department of Molecular Biophysics and Biochemistry at Yale University, earning a PhD in 2001. He performed postdoctoral research at The Scripps Research Institute, where he was awarded a Damon Runyon fellowship to study post-transcriptional regulation and ribonucleoprotein complex assembly. He joined the faculty of the UMass Chan Medical School in 2005, where he is now a Full Professor in the Department of Biochemistry and Molecular Biotechnology, as well as Vice-Chair for Outreach. Dr. Ryder's research focuses on the role of mRNA in reproductive biology in Caenorhabditis elegans. In his spare time, he is a singer-songwriter specializing in the Americana genre, releasing multiple singles, an EP, and one album to date.

More About Everyday RNA

This book describes the development of biological RNA therapeutics and their potential to transform modern medicine.

This book is meant to be accessible to anyone with a basic science education and an interest in RNA therapeutics. This includes students, policy makers, and potential patients. It is also intended as a reference for clinicians and researchers working in the field of RNA therapeutics. It can be used as a textbook for undergraduate or graduate students in molecular biology and genetics.

The book is intended to provide an honest appraisal of the potential of RNA medicine, the upsides as well as the challenges in an easy-to-understand format that will be useful to all. The author declares he has no finaiincial stake in the companies or therapeutics described in this book

A Brief Introduction to RNA Metabolism and Disease:

  • An RNA Primer
  • DNA, Chromosomes, and Genes
  • What is RNA?
  • DNA Decoded: Messenger RNA
  • How RNA Makes Proteins
  • Gene Regulation
  • Small Regulatory RNAs

    • Emerging RNA Therapeutics:
  • Biologicals vs. Chemicals
  • Antisense Oligonucleotide
  • Therapeutics
  • RNAi Therapeutics
  • mRNA Vaccines

    • RNA-Guided Genome Editing:
  • Rewriting the Genome
  • The CRISPR Revolution
  • The Ethics of Genome Editing
  • The Future of RNA Medicine

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    • * Prices subject to change without prior notice

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